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Neonatal GLP1R activation limits adult adiposity by durably altering hypothalamic architecture

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IV therapy is not recommended for those with kidney disease, congestive heart failure, active infection, uncontrolled hypertension, or known allergy to infusion components

for example, activating the leptin receptor to modulate energy homeostasis, e.g., reducing appetite while also blocking the response signal to reduce energy expenditure to enhance weight loss, utilise fat stores and thus preserve muscle

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