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Goutzourelas N et al

Smith JF, Shindel AW, Huang YC, et al

Temporal trend and attributable risk factors of stroke burden in China 1990-2019: an analysis for the global burden of disease study 2019

Some clinical studies have found elevated lactate levels (395, 396) in ME/CFS patient blood, cerebrospinal fluid, and muscles, suggesting there is reduced oxidative phosphorylation and a switch to anaerobic glycolysis (392, 397399)

Furthermore, NAC has been shown to increase taurine levels in skeletal muscle [68]

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