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Among the differentially expressed genes, 58 modules were identified as closely associated with microglial GLP-1R pathways and features of nerve injury, including pain hypersensitivity, ligation, paw withdrawal latency, and anxiety-related behaviors [64]
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No meaningful difference in fat loss was found between month one and baseline in these trials, highlighting why extended therapy is necessary
A prior study had shown that retatrutide and semaglutide reduced pancreatic tumor mass in mice, along with weight loss