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Int J Mol Sci 22(17):9592 Cuadrado A et al (2019) Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases

Mechanism of fat taste perception: association with diet and obesity

Introduction Glucagon-like peptide-1 (GLP-1) has been widely used to treat type 2 diabetes mellitus (T2 DM), with extant literature supporting its role in glycemic and appetite control (Andersen et al ., Reference Andersen, Lund, Knop and Vilsbll2018)

Phentermine, an appetite suppressant, rarely causes diarrhea but may produce dry mouth and constipation

By contrast, the companies have said the Phase 2 results will guide Phase 3 design and later-stage development