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Individual results vary depending on diet, exercise, dose and adherence

Precautions and considerations include: Personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2 (requires careful risk assessment) [1] Severe gastrointestinal disease Pregnancy or breastfeeding (use is not recommended

John, et al

A case report and survey

The potential value of combining these therapies lies in addressing overlapping cardiorenal and metabolic risk pathways as available evidence for dual therapy in HF populations remains limited and is derived largely from subgroup analyses, observational studies, and extrapolation from diabetes or obesity trials rather than dedicated HF randomized trials [24, 25, 27, 30, 50]