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This is because B12 is not a standard medication in the US or UK, so it is often made in small-scale compounding pharmacies rather than in large-scale manufacturing facilities
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The common protein must be taken in by macrophages or dendritic cells to start the process, causing an antigen presentation on MHC II molecules
But if you read the research, you will see that methyl B12 is best absorbed when dissolved in saline
Under medical supervision, Vitamin B12 replacement therapy helps restore adequate Vitamin B12 status and supports normal neurological and hematological function