Meanwhile, a post-hoc analysis of the STEP 1 and STEP 4 trials showed that semaglutide 2.4 mg was associated with an approximately 60% reduction of the 10-years risk of T2D according to the Cardiometabolic Disease Staging (CMDS) calculator, regardless of patients baseline glycemic status 74
Brookshire: Its a lot
We did not include achievement of at least a 5% reduction in body weight as an outcome because all doses of both drugs were superior to placebo in achieving at least a 10% weight reduction
Oral tirzepatide lozenge is a daily sublingual at roughly $239/mo
Out-of-Pocket Costs With Insurance Even when a plan covers Wegovy, cost-sharing can be significant: Tier 4 specialty copay: $75 to $150 per month with deductible met Before deductible: full negotiated price, often $1,100 to $1,250 With Novo Nordisk savings card stacked on commercial coverage: $0 to $25/month for eligible patients (see below) A 2023 JAMA Health Forum analysis of employer-sponsored plans found that only 27.6% of commercial plans included GLP-1 weight-loss coverage, so checking coverage before the first fill is essential
A little more effort may be required to administer Semaglutide once weekly, which can be a bit of a pain
