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Clinical trials have shown that patients can lose 15-20% of their body weight on average, making these among the most effective weight-loss medications ever developed
But not everyone wants surgery, and thats extremely expensive
Zhao TC: Glucagon-like peptide-1 (GLP-1) and protective effects in cardiovascular disease: a new therapeutic approach for myocardial protection
Using a method known as "target trial emulation," they compared patients initiating GLP-1 drugs with those initiating sodium-glucose cotransporter-2 (SGLT2) inhibitors or dipeptidyl peptidase-4 (DPP4) inhibitors
This result suggested that the long-acting form, unlike the short-acting forms (lixisenatide and exenatide), of exendin-4-based GLP-1RAs improved cardiovascular outcomes
Risk of gastroparesis in subjects with type 1 and 2 diabetes in the general population
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