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Up-regulation of iNOS in AML Blasts Creates an Immunosuppressive Microenvironment, Inhibits T-cell Proliferation and Transforms T-cells Towards a Tumor-tolerating Phenotype
Independent differential expression analysis was performed using DE-Seq2 and pathway analysis (GO, Reactome and KEGG) was conducted using differentially expressed genes in the studies
Schizophrenia Long-term use (up to 24 weeks) of 10003600 mg/day helped reduce negative symptoms (like low motivation, withdrawal)[1]

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This effect is dependent on phospholipase C activation and subsequent calcium release from IP 3 -sensitive intracellular stores [351]