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Shah and Vella, 2014)

In the UK, the Medicines and Healthcare products Regulatory Agency (MHRA) has licensed specific GLP-1 medications for use only in people who are obese, overweight with related health problems, or have type 2 diabetes

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report significant or concerning symptoms to your provider for ongoing monitoring

Common side effects include dry mouth, constipation, and a tingling sensation in the hands or feet

The key variable is whether you sustain semaglutide therapy, because weight regain typically begins 4-8 weeks after discontinuation as appetite normalizes