Boillee, S., Vande Velde, C
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High-sugar, high-fat (HSHF) diets significantly lead to an imbalance in the ratio of bacteria in the phylum Acidobacteria, Firmicutes and Thick-walled bacteria to those in the phylum Anaplasma, Aspergillus, Cyanobacteria, and Actinobacteria, which impairs the gut barrier function, and activates microglial cells in the brain, generating inflammation and affecting the cholinergic system to increase the risk of cognitive dysfunction (58, 59)
However, the extent of structural and functional abnormalities observed in tumor vessels vary greatly depending on the tumor type and anatomical location, and also within the same tumor depending on the tumor microenvironment
For example, for some patients with skin neuropathy accompanied by dry and rough skin, the moisturizing ingredients in the cream can moisturize the skin and alleviate skin discomfort
All analyses were performed using publicly available software tools, and analysis scripts are available from the corresponding author upon reasonable request