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The upregulated include the efflux pumps (PDR5, ERC1, SNQ2, FEX2), membrane transporters (PMA1, PNS1, YLR413w, PRM10, WSC2, FLC2), transcription factors (HCM1, SKN7, SMP1, TBF1), enzymes (KDX1, DBP8, HMT1, AAA1, IME2, YHR033W)

Consequently, the direct regulation of transporters and enzymes within metabolic pathways, as well as the indirect regulation of Gln metabolism through the modulation of associated oncogenes and ncRNAs, may represent promising avenues for future cancer therapies

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B12 can also be found as an additive to other foods, such as some fortified bread and plant-based milk