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In vitro, in differentiated human DA neurons, IR was associated with increased -synuclein and ROS levels, as well as mitochondrial depolarization, which may be mediated by polo-like kinase-2

You increase until you find the dose that works for you, whether that's 4mg, 8mg, or 12mg

Topiramate can cause metabolic acidosis (high blood acid), nephrolithiasis (kidney stones), and oligohidrosis (decreased sweating)

Unlike regular IGF-1, the LR3 modification prevents rapid binding to IGF-binding proteins, allowing greater biological availability and more consistent results

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Can physiotherapy prevent falls in older people