Integrative Medicine: A Clinician's Journal, 15 (1), 33
Combined research protocols allow investigators to examine whether co-administration produces additive effects on tissue-repair-relevant endpoints compared to either compound studied in isolation
Aebersold DM, Landt O, Berthou S, Gruber G, Beer KT, Greiner RH, et al
Further, MTX increased the expression of PERK (Figure 6B), GRP78 (Figure 6C), ATF4 (Figure 6D), and CHOP-10 (Figure 6E) in the liver compared to CTRL, indicating that ER stress is implicated in MTX-induced hepatotoxicity
a preliminary clinical study
Thus, there are different types of interneurons innervated by the same mossy fibers as well as interneurons of the same type receiving inputs from clearly distinct sources