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Therefore, please review this labeling carefully

Contrave, designed for oral administration, has variable bioavailability: naltrexone reaches about 96% bioavailability, while bupropion achieves approximately 87% bioavailability when taken with food

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Our focus is not merely on whether an effect is statistically significant, but rather on the magnitude of the effect size, the direction of cross-study fluctuations, and the underlying heterogeneityfactors that directly determine comparability and interpretative boundaries