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Palmatine, an isoquinoline alkaloid with lipid-regulating and anti-inflammatory properties, is a promising candidate

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However, in October 2024, the FDA declared the tirzepatide drug shortage over, so no compounded tirzepatide could be sold after March 19, 2025

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The safety and tolerability profile of the drug over the nearly 200-week trial was consistent with previous results of the 72-week benchmark in SURMOUNT-1

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