the authors reported a significant reduction in all-cause mortality (p=0.009) in the group of transplant recipients receiving steroids, treated with GLP-1 RAs, indicating a 38% lower risk of death compared to nonusers (55)
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Any new or worsening cardiac symptoms, significant muscle weakness, or altered consciousness warrants prompt medical evaluation
OTC medications that may help: One OTC medication that can help reduce histamine levels is diphenhydramine (Benadryl)
We excluded trials with a crossover design, non-inferiority studies comparing GLP-1RA to other drug classes without a placebo arm, or using withdrawn drugs
Some people may be drawn to the affordability of compounded semaglutide, hoping to manage costs through insurance