The maintenance of bloodbrain barrier homeostasis prevents the intrusion of ROS, neurotoxic debris, and inflammatory cytokines from disrupting the brain parenchyma
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Overall, treatment targeting juvenile worms resulted in smaller decreases in worm and egg burdens, which could be associated with higher ABC and MDR transporter activity in juvenile worms than adult worms 55
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Cyclical or targeted variations may be useful during the maintenance phase or for highly active individuals whose training demands benefit from periodic carbohydrate availability
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