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Description

Hypertension in rats is associated with an increased permeability of the colon to TMA, a gut bacteria metabolite

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Clinically significant safety concerns include heart rate elevation, risk of hypoglycaemia when combined with insulin or sulfonylureas, delayed gastric emptying, and a class-relevant caution regarding thyroid C-cell tumours

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It additionally provides methylsulfonylmethane (dimethyl sulfone)

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Another area of comparison is the convenience of use

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The exact incidence remains lowtypically less than 2% of usersbut individual cases do surface

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