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Glutamate is also known as an inhibitor of the cystine/glutamate antiporter, and the addition of elastin, a similar inhibitor, to lens epithelial cells induces ferroptosis, which is considered to be a contributing factor in cataracts 61

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Macrophage-derived IGF-1 promotes intestinal vascular endothelial cell proliferation in vivo in neonatal mice and protects against experimental NEC To examine the role of macrophage-derived IGF-1 on intestinal vascular endothelial cell proliferation in vivo, transgenic mice that express Cre recombinase driven by the Cx3cr1 promoter were bred with mice bearing loxP sites flanking exon 4 of the Igf 1 gene, to generate mice with IGF-1-deficient macrophages (Fig

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10.1038/s41598-019-48059-7 58 ChenH.GuoY.HuM.DuanW.ChangG.LiC

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