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Bile acid sequestrants (BASs) are anion exchange resins that prevent ileal uptake of bile acids by trapping BAs in the intestinal lumen, resulting in induced de novo synthesis of bile acids from cholesterol in the liver, which decreases plasma cholesterol

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Lithium amplifies agonist-dependent phosphatidylinositol responses in brain and salivary glands Biochem J 1982

If the carnitine shuttle is compromised, the heart and blood vessels cannot access the fatty acids they desperately need for fuel