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Most Common Side Effects Nausea tops the list

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Effectiveness Tirzepatide : Clinical studies show that Tirzepatide may lead to slightly greater weight loss than Semaglutide, with some patients losing up to 22.5% of their body weight

According to WebMD, headaches are one of the potential side effects

Jastreboff AM, Aronne LJ, Ahmad NN, Wharton S, Connery L, Alves B, Kiyosue A, Zhang S, Liu B, Bunck MC, et al

The American College of Sports Medicine recommends 200300 minutes of moderate-intensity aerobic exercise weekly for weight loss maintenance, significantly more than the 150 minutes suggested for general health