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Patients who are pregnant, planning pregnancy, or breastfeeding should discuss risks and alternatives with their clinician before use

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Posology and Method of Administration: The starting dose is 0.25 mg once a week for the first 4 weeks

In 1 patient, kidney biopsy showed advanced diffuse and nodular glomerulosclerosis accompanied by interstitial lymphoplasmacytic and eosinophilic infiltrate and evidence of acute tubular injury

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