BPC-157 is studied for its pro-angiogenic, fibroblast-activating, and anti-inflammatory properties across more than 100 independent pre-clinical publications covering tendon rupture, ligament tear, bone fracture, muscle injury, skin wound, and gastrointestinal tissue models
[DOI] [PMC free article] [PubMed] 10.Trujillo JM, Nuffer W, Smith BA
This question isnt completely settled yet
Fafula, Roman V et al
This is one reason a serum might cause breakouts months after you bought it but not when it was new
Abbreviations 1MT: 1-methyl-tryptophan 3HAA: 3-hydroxyanthranilic acid 3HK: 3-hydroxykynurenine 5-HT: Serotonin 7nAChRs 7: nicotinic acetylcholine receptors AHR: Aryl hydrocarbon receptor AMPAR: -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor BBB: Blood brain barrier BCG: Bacile Calmette-Gurin BDI-II: Beck Depression Inventory, 2nd edition BDNF: Brain-derived neurotrophic factor BSSI: Beck Scale for Suicidal Ideation CDRS-R: Childrens Depression Rating Scale-Revised CNS: Central nervous system ESBA: (S)-4-(ethylsulfonyl)benzoylalanine GBA: Gut-brain axis HAMD: Hamilton Depression Rating Scale HPA: Hypothalamic-pituitary-adrenal IDO: Indoleamine 2,3-dioxygenase KAT: Kynurenine aminotransferase KMO: Kynurenine 3-monooxygenase KP: Kynurenine pathway K-SADS-PL: Schedule for Affective Disorders and Schizophrenia for School-Age Children KYN: Kynurenine KYNA: Kynurenic acid LDH: Lactate dehydrogenase LPS: Lipopolysaccharide LSD: Lysergic acid diethylamide MDD: Major depressive disorder NMDAR: N-methyl-D-aspartate receptor NO: Nitric oxide PA: Picolinic acid QA: Quinolinic acid ROS: Reactive oxygen species SCFA: Short-chain fatty acids SSRI: Selective serotonin reuptake inhibitor TBI: Traumatic brain injury TDO : Tryptophan 2,3-dioxygenase TRP: Tryptophan UCMS: Unpredictable Chronic Mild Stress References Cipriani A, Furukawa TA, Salanti G, Chaimani A, Atkinson LZ, Ogawa Y, et al
