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OK, in all honesty this wasnt a truly guilt-free day (thats why its called a cheat day), but it was at least an eagerly anticipated moment of reprieve, where the cultural script temporarily loosened

The "black box" warning on these drugs is based on studies in rodents, who have different thyroid biology

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But this same mechanism can cause significant constipation , particularly at higher doses

By 3 months, improvement is clear