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Description

During an immune/inflammatory response a combination of enhanced utilization of cysteine for GSH synthesis and cell replication may be what leadsto a depletion of cellular SAM

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Randomisation and Study Treatment Participants were randomised in a 1:1 ratio to either active treatment with exenatide (Byetta) or placebo using a computer-generated randomisation list compiled by the Birmingham Clinical Trials Unit

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Targeting tumor-intrinsic hexosamine biosynthesis sensitizes pancreatic cancer to anti-PD1 therapy

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