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Mass spectrometry analysis of nitrotyrosinecontaining proteins

This is important, because tyrosine, and, hence, phenylalanine, is a precursor to melanin (94), and the symptoms of phenylalanine hydroxylase deficiency appear, to us, to be related to low melanin levels similar to PD: Parkinson-like symptoms, musty odor (95), and intellectual disability (cognitive problems)

doi: 10.1093/eep/dvac029 124 TownsendJ.PengZ.KizilaslanM.TaylorT.YangZ.AhsanN.et al

Oxidative stress: molecular perception and transduction of signals triggering antioxidant gene deffenses

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Harrisons Principles of Internal Medicine, 20e