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[DOI] [PMC free article] [PubMed] [Google Scholar] 58.Berthoud H.R
Certain medications mimic its effects to help people manage type 2 diabetes, and in some cases, lose weight
Jazet IM, Schaart G, Gastaldelli A, Ferrannini E, Hesselink MK, Schrauwen P, Romijn JA, Maassen JA, Pijl H, Ouwens DM, Meinders AE (2008) Loss of 50% of excess weight using a very low energy diet improves insulin-stimulated glucose disposal and skeletal muscle insulin signalling in obese insulin-treated type 2 diabetic patients
Compared to patients on Contrave, those on the GLP-1 drugs were 9.1 times more likely to have pancreatitis, 4.2 times more likely to have a bowel obstruction and 3.7 times more likely to develop gastroparesis, the study found