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Methimazole is an oral antithyroid drug that has recently attracted attention due to its depigmenting effect by inhibiting peroxidase, but it has also been shown to exert inhibitory effects on tyrosinase in experimental studies

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doi: 10.1038/ijo.2016.52 [DOI] [PMC free article] [PubMed] [Google Scholar] 33.ONeil PM, Aroda VR, Astrup A, et al

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DTC-specific RNAi against these genes had no effect on the extended lifespan upon the overexpression of tig-2 in DTC (Figs