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Human trials of GLP-1 medications in women with PCOS have found (2): Ovulation rates of 86% in women taking GLP-1s alongside metformin - compared to 29% on metformin alone, a threefold improvement 62% of women on GLP-1s had more regular menstrual cycles, versus 28% on placebo Significant reductions in testosterone levels These are meaningful numbers for a condition where restoring ovulation and cycle regularity remains one of the challenges

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[DOI] [PubMed] [Google Scholar] 56.Lowe WL Jr, Scholtens DM, Kuang A, et al

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Ontario Drug Benefit Formulary - Semaglutide ODB coverage criteria for Ozempic and Rybelsus (type 2 diabetes)