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Semaglutide's STEP trials (2021) sit alongside as GLP-1 comparators

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For example, the RNS nitric oxide (NO ) is produced from l-arginine by nitric oxide synthase, which then reacts with superoxide (O 2 ) to form peroxynitrite (ONOO) [15, 16]

Our results showed the increased expression of chondrogenic markers in GSH-high MSCs, including SOX9, COL2A1 , and ACAN