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This receptor is expressed in the anterior pituitary and hypothalamus and regulates pulsatile growth hormone secretion

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The trial also confirmed that the combination was well-tolerated, with gastrointestinal side effects being the most common adverse events

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Tirzepatide is FDA-approved and commercially available as Mounjaro (diabetes) and Zepbound (obesity), though supply constraints continue

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10.1016/j.mad.2016.04.005 [DOI] [PMC free article] [PubMed] [Google Scholar] Hou Y., Xie G., Miao F., Ding L., Mou Y., Wang I., et al

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Pajunen P, Rissanen H, Hrknen T, Jula A, Reunanen A, Salomaa V

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