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Future studies should investigate whether p53 ablation in adipocytes, with concomitant reduction in the abundance of AT macrophages, might lead to differences in weight (re-)gain after return to normal or obesogenic diet, to further test the hypothesis that adipocyte p53 is key in establishing an immuno-obesogenic memory of AT that promotes weight regain

Safety concerns include common gastrointestinal side effects, such as nausea and vomiting, as well as potential risks related to the pancreas, gallbladder, and thyroid C-cell tumors

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Yes, they share some physical responses like satiety, but it's best to have a discussion with a medical professional about what intervention would work best for you and your personal health goals