Overexpression of FSP1 or treatment with Fer-1, a ferroptosis inhibitor, significantly reversed the apoptosis, ferroptosis, and lipid peroxidation induced by the activation of the MPO/HOCl signaling pathway, exerting neuroprotective effects
Therefore, PEGylation now plays an important role in drug delivery, especially of peptide and protein based drugs, thus increasing their potential as therapeutic agents [11]
Cell Cycle 9 , 27192725 (2010)
Synthesis of bee venom loaded chitosan nanoparticles for anti-MERS-COV and multi-drug resistance bacteria
Accessed 8/10/2014
Minor side effects & safety profile While AOD 9604 appears to have a favorable tolerability profile in early trials, there are still relevant caution points: Reported/mild side-effects Injection-site reactions: redness, swelling, itching, mild pain