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While not really used in the medical world anymore, there is evidence that topical BPC 157 does in fact work

[6] Because IGF-1 LR3 retains strong IGF-1R affinity, it initiates the same receptor activation cascade the difference lies in bioavailability, not in the fundamental signaling logic

The "Wolverine stack" combines BPC-157 and TB-500 in the same protocol

For Twin Cities residents seeking long-term hormone optimization, this difference in cost can make consistent therapy more accessible while potentially providing more sustainable results

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doi: 10.1016/j.vph.2018.02.010