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It's clear these medications are changing the game for weight and diabetes management, and their effects in the brain are a big part of that

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Amylin analogs like cagrilintide work through the area postrema and nucleus tractus solitarius in the brainstem, a region that processes satiety signals through a completely separate neuronal network

This guide explains the GLP-1 vs GLP-2 distinction in plain terms, gives you a side-by-side comparison table, and untangles the "inhibitor" confusion so you know exactly what these medications are and what they do

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The decline in total testosterone (TT) is 1% per year and in free T 1.2% per year (which is caused by an increase in SHBG) [159]