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6.2.3.3 Cytokine dysregulation and myelin swelling Elevated levels of proinflammatory cytokines, such as TNF-, and reduced levels of epidermal growth factor have been observed in Vit B12-deficient states (Scalabrino et al., 2000)

doi: 10.1007/s12011-008-8117-8 43 SpallholzJEBoylanLMLarsenHS

Implication of the insulin-like growth factor-IR pathway in the resistance of non-small cell lung cancer cells to treatment with gefitinib

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Similar results were achieved by the same group through the inhibition of gelatinases and neutrophil elastase by CMT-3 in a porcine cardiopulmonary bypass and LPS-induced lung injury model