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STD 500 mg), LMG produced significantly higher iAUC and C max than STD ( p = 0.0064 and p = 0.0003, respectively), corresponding to approximately 2.49-fold higher incremental exposure and 2.43-fold higher peak response (Table 3)

4.6.2 Retinal disease Diabetic retinopathy (DR) is the most prevalent microvascular complication of diabetes and the leading cause of preventable blindness among working-age individuals (81)

GLP-1 was already on scientists' radar as a potential diabetes treatment it suppresses appetite and regulates blood sugar but there was a catch: the human body breaks it down almost immediately, making it useless as a drug

Pinckard RN, Hawkins D, Farr RS (1968) In vitro acetylation of plasma proteins, enzymes and DNA by aspirin

Thats really the central mechanism of action

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