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FIGURE 5 3.5 Upregulatory effect of glycitin on the expression of Nrf2 and Hmox1 genes In response to oxidative stress, the mRNA expression of Nrf2 and its downstream gene Hmox1 in the rat hippocampus and cerebellum, were measured by Real-time PCR

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The mechanism through which COCs exert their therapeutic effects involves the suppression of ovarian activity, reducing the estrogen-induced production of prostaglandins and therefore tissue inflammation [59]

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