Salvianolic acid B (from Salvia miltiorrhiza) protects cardiomyocytes during I/R by scavenging ROS and inhibiting apoptosis through PI3K/Akt and ERK pathways ( Limiting infarct expansion and fibrosis: After an MI, the reduction of infarct expansion and scar formation is crucial
Unlike other methods that analyse differential pathways between two phenotypical groups, the GSVA tool allows for computing an enrichment score (ES) of a given gene set in each sample, with a bimodal distribution of ES
Rapid oscillations in plasma glucagon-like peptide-1 (GLP-1) in humans: Cholinergic control of GLP-1
PMID: 7808246
In particular, clinical heterogeneity complicates the development of robust clinical endpoints, as small and fragmented patient populations often lack sufficient data to establish reliable outcome measures
Huang C, Yi H, Shi Y, Cao Q, Shi Y, Cheng D, Braet F, Chen XM, Pollock CA