NRF2 knockdown was found to suppress the expression of fatty acid oxidation genes ACOX1, ACOX2, CPT1, and CPT2 [77], and NRF2 activation in the mouse lung induces the expression of fatty acid oxidation genes and lipases
In this study, iFSP1 is a potent and selective inhibitor of FSP1 with an EC 50 of 103 nM
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doi: 10.3389/fnins.2020.601193 Received 31 August 2020 Accepted 04 November 2020 Published 08 December 2020 Volume 14 - 2020 Edited by John Zhang, Loma Linda University, United States Reviewed by Carmen Rubio, Instituto Nacional de Neurologa y Neurociruga Manuel Velasco Surez, Mexico