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Vitamin E -Glutathione level is significantly related to Vitamin E level, and supplementation with Vitamin E (100 IU/day) significantly increases Glutathione and lowers lipid per-oxidation and HbA1c concentrations in the erythrocytes of type 1 diabetic patients

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They also need careful interpretation

Avoid areas of broken, bruised, scarred, infected, or inflamed skin, and areas with moles or naevi

This gives flexibility on ratios but loses the documentation and reconstitution simplification of the pre-formulated blend