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The oral drug orforglipron (Foundayo) was also recently approved

lenta (SP5-62) is associated with l-carnitine consumption and SP2-71.3 is responsible for TMA production (Figure 7A)

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The most common adverse effects of metformin are gastrointestinal, including diarrhea, nausea, abdominal discomfort, and metallic taste, occurring in up to 30% of patients