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ALS monocyte-derived microglia-like cells reveal cytoplasmic TDP-43 accumulation, DNA damage, and cell-specific impairment of phagocytosis associated with disease progression

FIGURE 5 Ferroptosis, a regulatory cell death mode, is characterized by iron-dependent and lipid peroxide (LPO) accumulation, proposed by 2+ , which can produce OH through the Fenton reaction, and then react with polyunsaturated fatty acids in the plasma membrane to produce ROS, resulting in iron-regulated death

On the other hand, analysis of a Hey1-eGFP transgenic reporter mouse line shows more prominent GFP signal in the peri-arterial, SOX17 + side of the villus capillary network and in large mesenteric arteries, reflecting the known role of Notch signaling in arterial specification (Fig

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study demonstrated AHK-Cu's specific effects on hair follicle growth

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