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Lifestyle stress, and Neurodegeneration

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"Centenarians display plasma MOTS-c concentrations significantly higher than age-matched peers, a pattern that closely resembles levels found in individuals decades younger suggesting preserved mitochondrial signaling as a hallmark of exceptional longevity." The connection to cellular senescence deserves further attention here

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A total of 25 FES patients were recruited at Beijing Huilongguan Hospital

Conversely, excess haem-iron availability was shown to increase peak height and architectural complexity of NTHi biofilms following a period of haem-iron restriction (Szelestey et al., 2013)