Transient elastography in the diagnosis of pediatric non-alcoholic fatty liver disease and its subtypes
While further investigation is warranted, it could be that GHK has anti-aging effects similar to rapamycin
14 BruixJ.QinS.MerleP.GranitoA.HuangY
Why Vitamin B12 Deficiency Is Often Missed in Aging Adults Vitamin B12 deficiency is often missed because the symptoms fatigue, anemia, neuropathy, memory problems, or walking difficulties are quite common in older adults, and can easily be caused by something else
side effects may affect eating Percentage : Approximately 0.5-2% body weight lost for 220-pound individual Weeks 5-8 (First Dose Increase): Expected : 3-7 additional pounds lost Cumulative : 4-11 pounds total from baseline Why More Loss : Higher dose provides stronger appetite suppression Percentage : Approximately 2-5% cumulative body weight lost Weeks 9-12 (Second Dose Increase): Expected : 3-7 additional pounds lost Cumulative : 7-18 pounds total from baseline Percentage : Approximately 3-8% cumulative body weight lost Milestone : Many members notice clothing fitting differently, others commenting Months 4-6 (Continued Escalation): Expected : 1-2 pounds weekly average Cumulative : 15-30 pounds total from baseline Percentage : Approximately 7-14% cumulative body weight lost Milestone : Significant visible changes, substantial health improvements Months 7-12 (Maintenance Dose Phase): Expected : 0.5-1.5 pounds weekly average (rate slows) Cumulative : 30-45 pounds total from baseline Percentage : Approximately 14-20% cumulative body weight lost (if reaching clinical trial averages) Milestone : Major health transformations, lifestyle adaptations Beyond 12 Months : Rate typically slows significantly or plateaus Focus shifts from loss to maintenance Continued medication typically required to maintain results May achieve additional modest losses with continued treatment Important Expectations : These are averages : Individual results vary dramatically Not linear : Weight loss occurs in irregular pattern (stalls, whooshes, plateaus) Water weight fluctuations : Daily scale fluctuations 2-4 pounds normal (water, not fat) Plateaus normal : Multi-week plateaus common
These results suggest that while the AS treatment initially enhances the O phase but later reduces the J, I, and P phases, the combined treatment (AS + FeNP) reverses this effect and maximizes fluorescence intensity and amplitude across all OJIP phases
