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After 5 days at 0.25mg with no adverse effects, the protocol advances to 0.5mg daily for another 57 days

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The flow rate was kept at 1.0 mL/min

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WalkerMEODonnellAAHimaliJJRajendranIMelo van LentDAtaklteFet alAssociations of the Mediterranean-dietary approaches to stop hypertension intervention for neurodegenerative delay diet with cardiac remodelling in the community: the Framingham heart study