In comparing CC with DC, decompensation is significantly associated with worsening components of SF-36 including PCSS (MD of 6.79, 95% CI of 4.54 to 9.05, random effect, I2 = 87%, P 18.3)
For others, side effects may be minimal or none and weight loss slow down after an initial large loss
A simple weekly log works
"So we also have to really make sure that we turn these positive moments that right now we're in into a longer term trend, so we gain the trust day by day and improve that both internally as well as, of course, externally, and I will work hard to make sure that this continues."
and E-selectin, P-selectin, PDGF and ICAM-I (coagulant- inducible e.g., by thrombin, Factor IX/DCa, Factor X/Xa and/or plasmin)
The severity typically peaks during dose escalation and often improves as the body adjusts to the medication