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Oral small molecule inhibitors, such as JAK inhibitors, provide a viable alternative to injections while still being effective

That is the difference between medicine and marketing

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Sources: Reinwald, C., Schauer, C., Csepregi, J., Kienhfer, D., Weidner, D., Malissen, M., Mocsai, A., Schett, G., Herrmann, M

A 2024 analysis of adverse event reports found that depression-related complaints represented less than 2% of all GLP-1 side effect reports, making it an uncommon but documented concern

WHAT'S CHANGING Zepbound vs Saxenda: 2026 Outlook 2026: Saxenda Losing Market Share As newer GLP-1s like Zepbound and Wegovy show superior efficacy, Saxenda (FDA-approved since 2014) is gradually being replaced on formularies