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Additionally, it has been discovered that C-KIT inhibitor imatinib harbors high efficacy against melanoma with KIT mutations, but not with KIT amplification only (54% vs 0% partial response) (148, 150)

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Furthermore, we observed a reduction in TH1-related cytokines after GE2 treatment in SD-fed rats (F( 1,25 ) = 5.527, R 2 = 0.101, p = 0.010

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